• Jan-P Breuer, Vera von Dossow, Christian von Heymann, Markus Griesbach, Michael von Schickfus, Elise Mackh, Cornelia Hacker, Ulrike Elgeti, Wolfgang Konertz, Klaus-D Wernecke, and Claudia D Spies.
• Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow-Klinikum, Berlin, Germany.
• Anesth. Analg. 2006 Nov 1;103(5):1099-108.

AbstractIn this study we investigated the effects of preoperative oral carbohydrate administration on postoperative insulin resistance (PIR), gastric fluid volume, preoperative discomfort, and variables of organ dysfunction in ASA physical status III-IV patients undergoing elective cardiac surgery, including those with noninsulin-dependent Type-2 diabetes mellitus. Before surgery, 188 patients were randomized to receive a clear 12.5% carbohydrate drink (CHO), flavored water (placebo), or to fast overnight (control). CHO and placebo were treated in double-blind format and received 800 mL of the corresponding beverage in the evening and 400 mL 2 h before surgery. Patients were monitored from induction of general anesthesia until 24 h postoperatively. Exogenous insulin requirements to control blood glucose levels

26 keywords...

hide…