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Curr. Hypertens. Rep. · Dec 2006
ReviewPathophysiology and medical management of systemic hypertension in preeclampsia.
- William H Frishman, Megan Veresh, Stacy J Schlocker, and Nergesh Tejani.
- Department of Medicine, New York Medical College, Valhalla, NY 10595, USA. william_frishman@nymc.edu
- Curr. Hypertens. Rep. 2006 Dec 1;8(6):502-11.
AbstractHypertension that complicates preeclampsia in pregnancy is a disorder that requires special consideration in both prevention and pharmacologic treatment. In recent years, few advances have been made regarding the pathophysiology and prevention of preeclampsia; however, there have been some promising results from studies on possible modes of screening women for preeclampsia before clinical signs and symptoms are apparent. The recommendations for first-line drug therapy for the hypertensive complications of preeclampsia have changed little, primarily because first-line medications have had the advantage of extensive research experience. Recent clinical trials have demonstrated the efficacy and safety of various second-line drugs for the hypertensive complications of preeclampsia; whether these therapies can eventually replace the standard recommended first-line medications will require more extensive long-term investigation.
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