• David Hoppenstein, Edna Zohar, Erez Ramaty, Shay Shabat, and Brian Fredman.
• Department of Anesthesiology and Intensive Care, Meir Hospital, Kfar Saba 44281, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
• J Clin Anesth. 2005 Sep 1;17(6):431-8.

Study ObjectiveTo assess the effect of regional vs general anesthesia on transcranial cerebral oxygen saturation (rSo2).DesignProspective, randomized, open-label study.SettingLarge referral hospital.PatientsSixty American Society of Anesthesiologists physical status I, II, and III geriatric patients at least 60 years of age, undergoing surgical fixation of the neck of femur.InterventionsPatients were randomized to receive either general (group GA) or spinal (group S) anesthesia. In all cases, frontal rSo2 was measured for a 10-minute preoperative control period, throughout the surgical procedure, and for 10 minutes postoperatively.Measurement And Main ResultsThe frequency of a decrease in rSo2 below baseline preoperative levels was significantly (P < .0001) higher in group S. However, the number of patients in whom at least one dip below baseline was recorded was similar between the groups. By contrast, general anesthesia was associated with a significantly higher rSo2 when compared with spinal anesthesia. Logistic regression revealed no correlation between changes in blood pressure, heart rate, or peripheral oxygen saturation and the frequency of rSo2 dips below baseline.ConclusionCerebral oxygen saturation is likely patient specific and independent of the anesthetic technique administered. Spinal anesthesia is associated with a higher incidence of cerebral desaturation. However, the number of patients in whom at least one dip below baseline was recorded was similar between the groups.

20 keywords...

hide…