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Critical care clinics · Apr 2013
ReviewPediatric intensive care treatment of uncontrolled status epilepticus.
- Ryan Wilkes and Robert C Tasker.
- Division of Critical Care, Department of Anesthesia, Pain and Perioperative Medicine, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.
- Crit Care Clin. 2013 Apr 1;29(2):239-57.
AbstractThe critically ill mechanically ventilated child with ongoing seizures that are refractory to any treatment presents a distinct challenge in pediatric neurocritical care. The evidence base from randomized controlled trials on which anti-epileptic drug (AED) strategy should be used is inadequate. This review of refractory and super-refractory status epilepticus summarizes recent pediatric case series regarding definitions, the second-tier AED therapies once initial anticonvulsants have failed, and the experience of high-dose midazolam, barbiturate anesthesia, and volatile anesthetics for uncontrolled status epilepticus.Copyright © 2013 Elsevier Inc. All rights reserved.
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