• Critical care medicine · Apr 2004

    Review

    Assessment and management of patients with ischemic heart disease.

    • Shamsuddin Akhtar and David G Silverman.
    • Department of Anesthesiology, Yale University School of Medicine, New Haven, CT, USA.
    • Crit. Care Med. 2004 Apr 1;32(4 Suppl):S126-36.

    ObjectiveReview the perioperative management of patients who are scheduled for noncardiac surgery.Data SourceReview of literature (PubMed, MEDLINE).ConclusionsPatients with ischemic heart disease who undergo noncardiac surgery are at significant risk of perioperative cardiac morbidity and mortality. Recent joint guidelines from the American College of Cardiology and American Heart Association have significantly streamlined the preoperative evaluation processes. Augmented hemodynamic control with intensive perioperative pharmacologic therapy with beta-blockers and possibly alpha-2 agonist has been shown to improve perioperative cardiovascular outcomes. However, translating this information to clinical practice continues to be a challenge and requires a multi- disciplinary approach. A particular intraoperative anesthetic technique is unlikely to influence perioperative cardiac morbidity and mortality. Postoperative management with goals of decreasing hemodynamic stress is important in patients with ischemic heart disease. Diagnosis and management of perioperative myocardial infarction continues to be a challenge. However, use of cardiac specific biomarkers should improve the diagnostic process.

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