• Comput Math Methods Med · Jan 2015

    Tactics and strategies for managing Ebola outbreaks and the salience of immunization.

    • Wayne M Getz, Jean-Paul Gonzalez, Richard Salter, James Bangura, Colin Carlson, Moinya Coomber, Eric Dougherty, David Kargbo, Nathan D Wolfe, and Nadia Wauquier.
    • Department of Environmental Science, Policy, and Management, University of California, Berkeley, CA 94720, USA ; School of Mathematical Sciences, University of KwaZulu-Natal, Private Bag X54001, Durban 4000, South Africa.
    • Comput Math Methods Med. 2015 Jan 1;2015:736507.

    AbstractWe present a stochastic transmission chain simulation model for Ebola viral disease (EVD) in West Africa, with the salutary result that the virus may be more controllable than previously suspected. The ongoing tactics to detect cases as rapidly as possible and isolate individuals as safely as practicable is essential to saving lives in the current outbreaks in Guinea, Liberia, and Sierra Leone. Equally important are educational campaigns that reduce contact rates between susceptible and infectious individuals in the community once an outbreak occurs. However, due to the relatively low R 0 of Ebola (around 1.5 to 2.5 next generation cases are produced per current generation case in naïve populations), rapid isolation of infectious individuals proves to be highly efficacious in containing outbreaks in new areas, while vaccination programs, even with low efficacy vaccines, can be decisive in curbing future outbreaks in areas where the Ebola virus is maintained in reservoir populations.

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