• Cleve Clin J Med · Jun 2000

    Acute respiratory distress syndrome: low-stretch ventilation improves survival.

    • H P Wiedemann and A C Arroliga.
    • Department of Pulmonary and Critical Care Medicine, Cleveland Clinic, USA. wiedemh@ccf.org
    • Cleve Clin J Med. 2000 Jun 1;67(6):435-40.

    AbstractIn a recent major study, patients with acute respiratory distress syndrome or acute lung injury were randomly assigned to have their respirators set to deliver tidal volumes of either 6 mL/kg or a more-traditional 12 mL/kg. Mortality in the low-tidal-volume group was 31.0%, compared with 39.8% in the traditional-tidal-volume group, a 22% difference (P = .007).

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