• Br J Anaesth · Dec 2002

    Case Reports

    Intrathecal morphine overdose during combined spinal-epidural block for Caesarean delivery.

    • M Cannesson, N Nargues, B Bryssine, R Debon, E Boselli, and D Chassard.
    • Service d'Anesthésie-Réanimation, Hôpital de l'Hôtel-Dieu, F-69002 Lyon, France.
    • Br J Anaesth. 2002 Dec 1;89(6):925-7.

    AbstractWe describe a 25 mg intrathecal morphine overdose during a combined spinal-epidural block for a Caesarean delivery. Naloxone infusion (5.24 mg over 24 h) was started prior to the patient becoming symptomatic and almost immediately after the overdose. Invasive therapeutics such as mechanical ventilation were avoided.

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