• T Steffen, R Warschkow, M Brändle, I Tarantino, and T Clerici.
• Department of Surgery, Kantonsspital St Gallen, St Gallen, Switzerland. Thomas.Steffen@kssg.ch
• Br J Surg. 2010 Jul 1;97(7):1000-6.

BackgroundBilateral superficial cervical block during thyroid surgery can reduce postoperative pain but its value is unclear. This randomized clinical trial assessed the efficacy of such regional anaesthesia on postoperative pain after thyroid surgery performed under general anaesthesia.MethodsPatients undergoing thyroid surgery were randomized to one of four groups in a double-blind fashion. Patients received a cervical block with placebo or bupivacaine at the start or end of surgery. Postoperative pain, analgesic use and length of hospital stay were assessed.ResultsThere were 159 patients eligible for analysis. The bupivacaine group had significantly less pain than the placebo group (P = 0.016). The timing of bupivacaine administration did not significantly influence pain (preoperative versus postoperative, P = 0.723). There was no difference between groups in the amount of analgesic used. Length of hospital stay was the same in the bupivacaine and placebo groups (P = 0.925) and when bupivacaine was administered at the beginning or end of surgery (P = 0.087).ConclusionBilateral superficial cervical block with bupivacaine combined with general anaesthesia significantly reduced postoperative pain after thyroid surgery.Registration NumberNCT00472446 (http://www.clinicaltrials.gov).Copyright (c) 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. Copyright 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.

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