• Am. J. Crit. Care · Nov 2011

    Bispectral index monitoring in the management of sedation in an intensive care unit patient with locked-in syndrome.

    • Sadeq A Quraishi, Sandralee A Blosser, and Robert A Cherry.
    • Harvard Medical School, Boston, Massachusetts, USA. squraishi@partners.org
    • Am. J. Crit. Care. 2011 Nov 1;20(6):487-90.

    AbstractLocked-in syndrome is an extremely rare neurological state caused by injury of the ventral pons. The syndrome is characterized by quadriplegia and anarthria with concomitant preservation of cortical function. When a reversible underlying pathological abnormality is identified and managed aggressively, meaningful recovery is possible. Because patients retain consciousness throughout their illness, a dependable method for titrating sedation may improve their quality of life. The case presented suggests that bispectral index monitoring may be a cost-effective and reliable method for managing sedation in patients with locked-in syndrome.

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