• Curr Pain Headache Rep · Apr 2001

    Review

    Complex regional pain syndromes.

    • R Baron and G Wasner.
    • Klinik für Neurologie, Christian-Albrechts-Universität Kiel, Niemannsweg 147, Kiel 24105, Germany. r.baron@neurologie.uni-kiel.de
    • Curr Pain Headache Rep. 2001 Apr 1; 5 (2): 114-23.

    AbstractComplex regional pain syndromes (CRPS) (formerly reflex sympathetic dystrophy and causalgia) are neuropathic pain conditions that are initiated by an extremity trauma or peripheral nerve lesion. Clinical definition and scientific understanding of CRPS are still evolving; however, both the clinical picture and therapeutic options are significantly influenced by a dysfunction of the sympathetic nervous system. Recent investigations suggest functional central abnormalities and a peripheral inflammatory component in the pathophysiology of CRPS. Interdisciplinary treatment includes physical, pharmacologic, and invasive interventional therapy, as well as stimulation techniques.

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