• B Mihai, Cristina Lăcătuşu, and Mariana Graur.
• Universitatea de Medicină si Farmacie Gr T Popa Iaşi, Facultatea de Medicină, Centrul Clinic de Diabet, Nutriţie si Boli Metabolice.
• Rev Med Chir Soc Med Nat Iasi. 2008 Apr 1;112(2):321-6.

AbstractAlcoholic ketoacidosis is an acute metabolic acidosis that typically occurs in people who chronically abuse alcohol and have a recent history of binge drinking, little or no food intake and persistent vomiting. Alcoholic ketoacidosis is a result of starvation with glycogen depletion and counter-regulatory hormone production, a raised nicotinamide adenine dinucleotide (NADH) to nicotinamide adenine dinucleotide (NAD+) ratio related to the metabolism of ethanol, and volume depletion resulting in ketogenesis. Alcoholic ketoacidosis is characterized by elevated serum ketone levels and a high anion gap. Once the diagnosis of alcoholic ketoacidosis is made, the mainstay of treatment is hydration with 5% dextrose in normal saline. With timely and aggressive intervention, the prognosis for a patient with alcoholic ketoacidosis is good.

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