• Clin Neuropharmacol · May 2007

    Case Reports

    Refractory hiccup: successful treatment with gabapentin.

    • Hortensia Alonso-Navarro, Lluisa Rubio, and Félix Javier Jiménez-Jiménez.
    • Sección de Neurología, Hospital Virgen de la Concha, Zamora, Spain.
    • Clin Neuropharmacol. 2007 May 1;30(3):186-7.

    ObjectiveTo report a patient with intractable hiccup which improved with gabapentin.Case ReportA 69-year-old woman diagnosed with refractory hiccup that started 50 years before improved dramatically after a trial of gabapentin for essential tremor. Gabapentin withdrawal led to reappearance of hiccup, which improved again after its reintroduction.ConclusionsGabapentin should be considered as a possible therapy for refractory hiccup.

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