• Gan To Kagaku Ryoho · Nov 2014

    Case Reports

    [Efficiency of pre-operative chemoradiotherapy in treating a case of advanced rectal cancer].

    • Atsushi Tamura, Katsunori Ami, Ayako Watanabe, Junnosuke Hayasaka, Kentaro Takagi, Eiko Okamoto, Akiko Kitazume, Mayumi Kondou, Kentaro Gokita, Kenichiro Imai, Shikofumi Tei, Masayuki Ando, Kuniyuki Arai, and Takao Shibayama.
    • Dept. of Gastroenterology, Tokyo Metropolitan Toshima Hospital.
    • Gan To Kagaku Ryoho. 2014 Nov 1;41(12):1566-8.

    AbstractThere is insufficient evidence for the pre-operative use of chemoradiotherapy (CRT) in treatment of advanced rectal cancers, and its efficiency and safety are unclear. However, it has recently been suggested that a new class of carcinostatic agents are more effective during preoperative CRT. Under the National Comprehensive Cancer Network (NCCN) guidelines, 5-FU and capecitabine have been recommended as the standard drugs for use during combination chemoradiotherapy. The Japanese Society for Cancer of Colon and Rectum (JSCCR) guidelines for 2014 also recommend the use of both drugs during preoperative CRT. We report a case of rectal cancer, which was successfully treated with radical resection and neoadjuvant chemoradiotherapy.

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