• JAMA · Dec 2015

    Comment

    Interventions for Rosacea.

    • Esther J van Zuuren and Zbys Fedorowicz.
    • Department of Dermatology, Leiden University Medical Centre, Leiden, the Netherlands.
    • JAMA. 2015 Dec 8;314(22):2403-4.

    Clinical QuestionWhich interventions are associated with highest efficacy and fewest adverse events for treating rosacea?Bottom LineThere is high-quality evidence that topical brimonidine, azelaic acid, and ivermectin, as well as oral doxycycline and isotretinoin, are associated with improvements in rosacea. Lower-quality evidence is available for topical metronidazole, oral tetracycline, laser and light-based therapy, and topical cyclosporine for ocular rosacea. Most treatments are not associated with higher adverse event rates than placebo.

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