• Critical care medicine · Jun 2012

    Review

    Treatment of acute coronary syndrome: part 2: ST-segment elevation myocardial infarction.

    • Richard A Lange and Jeffrey C Trost.
    • Johns Hopkins School of Medicine, Baltimore, MD, USA. jtrost2@jhmi.edu
    • Crit. Care Med.. 2012 Jun 1;40(6):1939-45.

    ObjectiveFamiliarize clinicians with recent information regarding the diagnosis and treatment of ST-segment elevation myocardial infarction.Data SourcesPubMed search and review of relevant medical literature.SummaryDefinition, pathophysiology, clinical presentation, diagnosis, and treatment of ST-segment elevation myocardial infarction are reviewed.ConclusionsPatients with ST-segment elevation myocardial infarction benefit from prompt reperfusion therapy. Adjunctive antianginal, antiplatelet, antithrombotic, beta blocker, angiotensin-converting enzyme inhibitor, and statin agents minimize ongoing cardiac ischemia, prevent thrombus propagation, and reduce the risk of recurrent cardiovascular events.

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