• Br J Ophthalmol · Jul 2013

    Randomized Controlled Trial Comparative Study

    Oral gabapentin premedication for elderly patients undergoing intraocular surgery.

    • J Kavitha, Satyen Parida, Pankaj Kundra, and Renuka Srinivasan.
    • Department of Anesthesiology & Critical Care, JIPMER, Dhanvantari Nagar, Puducherry, India.
    • Br J Ophthalmol. 2013 Jul 1;97(7):900-4.

    AimsTo compare effects of gabapentin premedication with diazepam in patients undergoing cataract surgery.MethodsIn a randomised double-blind study, the effects of gabapentin premedication as a sedative, anxiolytic, analgesic and oculohypotensive agent were studied in 56 elderly patients undergoing elective intraocular surgery.ResultsThere was significantly more sedation in the diazepam group than in the gabapentin group. However, there was less subjective anxiety in the gabapentin group than in the control group. There was a significant fall in intraocular pressure (IOP) and significant reduction in mean arterial pressure in the gabapentin group compared with the control group. Perioperatively, significantly more supplementation with intravenous midazolam was given in the control group than in the gabapentin group. A significantly larger number of patients in the gabapentin group scored a postanaesthesia recovery score of 10 compared with the control group. There was a statistically significant difference in the postoperative visual analogue scale scores for pain and number of analgesic requests with gabapentin scoring over diazepam in this regard.ConclusionsHence, premedication with oral gabapentin in these elderly patients undergoing elective intraocular surgery produced intraoperative anxiolysis, decreased sedation, a modest decrease in IOPs and improved postoperative recovery.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…