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Forensic Sci Med Pathol · Jan 2008
Case ReportsFatal bupropion overdose with post mortem blood concentrations.
- Henry A Spiller, Edward Bottei, and Linda Kalin.
- Kentucky Regional Poison Center, P.O. Box 35070, Louisville, KY 40232-5070, USA. henry.spiller@nortonhealthcare.org
- Forensic Sci Med Pathol. 2008 Jan 1;4(1):47-50.
AbstractWe report five cases of fatal bupropion overdose with post mortem bupropion concentrations ranging from 3.1 to >20 mg/L. Four patients had ingested a sustained-release formulation of bupropion and had evidence of pill "bodies" in their stomach with significantly elevated blood bupropion concentrations. The pills found in these patients may represent the residual matrix/shell with significant portions of the actual bupropion released and absorbed by the patients.
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