• Sarcoidosis Vasc Dif · Oct 2011

    Case Reports

    Successful pregnancy complicated by persistent pneumothorax in a patient with lymphangioleiomyomatosis (LAM) on sirolimus.

    • M Faehling, S Frohnmayer, M Leschke, B Trinajstic-Schulz, J Weber, and F Liewald.
    • Klinik für Kardiologie und Pneumologie, Klinikum Esslingen, Esslingen; 2Lungenfacharztpraxis, Esslingen. m.faehling@klinikum-es.de
    • Sarcoidosis Vasc Dif. 2011 Oct 1;28(2):153-5.

    AbstractWe report a successful pregnancy in a patient with longstanding LAM on treatment with sirolimus. During temporary discontinuation fo sirolimus in early pregnancy, lung function declined but recovered after resumption of sirolimus. Pregnancy was complicated by a persistent pneumothorax which was treated surgically postnatally. The child has had a normal development despite exposure to low dose sirolimus intermittently during early embryonal and mid-fetal life.

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