• Lancet neurology · May 2008

    Review

    Metastatic epidural spinal cord compression.

    • John S Cole and Roy A Patchell.
    • Department of Neurosurgery, University of Kentucky Medical Center, Lexington, KY 40536, USA.
    • Lancet Neurol. 2008 May 1;7(5):459-66.

    AbstractMetastatic epidural spinal cord compression (MESCC) occurs when cancer metastasises to the spine or epidural space and causes secondary compression of the spinal cord. MESCC is a common complication of malignancy that affects almost 5% of patients with cancer. The most common symptom is back pain. MESCC is a medical emergency that needs rapid diagnosis and treatment if permanent paralysis is to be prevented: the diagnosis of MESCC is best made with MRI; and corticosteroids, radiation therapy, and surgery are all established treatments. Future research will focus on prevention, improving detection, and the development of new treatments.

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