• J Intensive Care Med · Jan 2015

    Review Case Reports

    Hypertonic saline in elevated intracranial pressure: past, present, and future.

    • Salim Surani, Geoff Lockwood, Melissa Y Macias, Bharat Guntupalli, and Joseph Varon.
    • Division of Pulmonary and Critical Care Medicine, Texas A&M University, TX, USA srsurani@hotmail.com.
    • J Intensive Care Med. 2015 Jan 1;30(1):8-12.

    AbstractHypertonic Saline (HS) has been a proven and effective therapy and a safe alternative to mannitol in patients with increase intracranial pressure (ICP). We hereby present a case of 25-year-old women with intracranial bleed secondary to right parietal arteriovenous malformation. Patient underwent surgery for evacuation of hematoma and resection of arteriovenous malformation. Post- operative course was complicated by recurrent episodes of elevated ICP. She received total of 17 doses of 23.4% HS and 30 doses of mannitol with good outcome. Despite reluctance from some clinicians to use HS, hypertonic saline seems to be a safe and effective therapy.© The Author(s) 2013.

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