• J Low Genit Tract Dis · Jan 2007

    Human papillomavirus detection in urine samples: an alternative screening method.

    • Francesc Alameda, Beatriz Bellosillo, Pere Fusté, Mercè Musset, Maria-Luisa Mariñoso, Gemma Mancebo, Maria Teresa Lopez-Yarto, Ramon Carreras, and Sergi Serrano.
    • Department of Pathology, University Hospital del Mar, Autonomous University of Barcelona, Barcelona, Catalonia, Spain. 86780@imas.imim.es
    • J Low Genit Tract Dis. 2007 Jan 1;11(1):5-7.

    ObjectivesTo investigate the usefulness of human papillomavirus detection in the urine of women with poor gynecologic attention.Materials And MethodsFifty urine and 50 cervical samples from 50 women were analyzed. Polymerase chain reaction was performed on these 100 samples using consensus primers and a low-density microarray-based method for human papillomavirus typing.ResultsThe concordance of the results between both sample groups was 80%. In the urine samples, the sensitivity of polymerase chain reaction for high-grade squamous intraepithelial lesion was 100%, the specificity was 80%, the positive predictive value was 91%, and the negative predictive value was 100%.ConclusionsHuman papillomavirus detection in urine samples may be used as an alternative screening method for women with poor gynecologic attention.

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