• Crit Care · Jan 2016

    Acute kidney stress-a useful term based on evolution in the understanding of acute kidney injury.

    • Nevin Katz and Claudio Ronco.
    • Division of Cardiac Surgery, Johns Hopkins University, 1800 Orleans Street, Suite 7107, Baltimore, MD, 21287, USA. nevinkatz@aol.com.
    • Crit Care. 2016 Jan 22; 20: 23.

    AbstractCritical care physicians have debated an appropriate term for the clinical phase preceding acute kidney injury (AKI). The recent development of cell cycle arrest biomarkers that signal the potential development of AKI is part of an evolution in the molecular diagnosis and understanding of AKI. It is proposed that the pre-injury phase that leads to AKI can be described as "acute kidney stress". This term has the potential to expand horizons in regard to the early detection of situations that will lead to AKI and the early implementation of corrective measures.

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