• Pediatric emergency care · May 2013

    Case Reports

    Status epilepticus in a child secondary to ingestion of skin-lightening cream.

    • Edward W Boyer, Sean Rhyee, Mariann Manno, and Jarrett M Burns.
    • Division of Medical Toxicology, Department of Emergency Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA. drjburns@gmail.com
    • Pediatr Emerg Care. 2013 May 1;29(5):662-4.

    AbstractThe popularity of the Internet and online media has led to the increased availability of prescription-strength, skin-lightening products contributing to a rise in their use among people with various skin pigment disorders. These products may contain a wide variety of active ingredients such as heavy metals, hydroquinone, and corticosteroids that can be highly toxic, especially after prolonged application. For decades, there have been case reports of both corticosteroid and heavy metal toxicity related to skin-lightening cream use. We report a case of a child who developed status epilepticus after ingesting a skin-lightening solution containing 2% hydroquinone. The toxicodynamics of hydroquinone and its effects on the central nervous system are discussed.

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