• J. Clin. Virol. · Jun 2008

    Case Reports

    Detection of enteroviral RNA on Guthrie card dried blood of a neonate with fatal Coxsackie B3 myocarditis on day 17.

    • Koenraad Smets, Annelies Keymeulen, Elke Wollants, Katrien Lagrou, Marc Van Ranst, and Elizaveta Padalko.
    • Department of Neonatology, Ghent University Hospital, De Pintelaan 185, B-9000 Gent, Belgium. koenraad.smets@ugent.be
    • J. Clin. Virol. 2008 Jun 1;42(2):207-10.

    AbstractA fatal case of Coxsackie B3 myocarditis in a neonate is described. The clinical features became evident in the 3rd week of life, but enteroviral RNA was detected in the dried blood spot of the baby collected on day 4 after birth. This is the first report on the detection of enteroviral RNA in Guthrie card dried blood using reverse-transcriptase PCR. Materials and methods used are described in detail.

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