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Randomized Controlled Trial Clinical Trial
[Intravenous anesthesia using continuous administration of propofol and fentanyl: fentanyl administration procedure and quality of awareness].
- Yoko Yamazaki, Teruhito Kunimatsu, Koji Takada, Syunichi Oka, Noriya Hirose, and Toru Misaki.
- Department of Dental Anesthesiology, Nihon University School of Dentistry, Tokyo 101-8310.
- Masui. 2003 Jun 1;52(6):626-30.
BackgroundWe studied total intravenous anesthesia using continuous administration of propofol and fentanyl and examined especially the method of fetanyl administration.MethodsAnesthesia was induced with fentanyl 2 micrograms.kg-1 and propofol 2 mg.kg-1. Fentanyl 1 microgram.kg-1 was then administered before the start of the operation and infused continuously at a rate of 0.02 microgram.kg-1.min-1 during operation. Propofol was also infused continuously at 4-10 mg.kg-1.min-1.ResultsThese methods allowed a significant reduction in the necessary dose of fentanyl and propofol compared with ordinary methods, and a stable general condition was maintained during the operation. Additionally, high quality of awareness was obtained after the recovery.ConclusionsThis continuous administration procedure of fentanyl reduced the total doses of both propofol and fentanyl, allowing high quality of awareness after the recovery.
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