• J A Leitch, N Sutcliffe, and G N C Kenny.
• Glasgow Dental Hospital and School, Glasgow. leitch@bigfoot.com
• Br Dent J. 2003 Jan 11;194(1):43-5.

ObjectiveTo assess the safety and efficacy of a new patient-maintained propofol system for conscious sedation in dentistry.DesignProspective clinical trialSettingDepartment of Sedation, Glasgow Dental Hospital and School, 2001Subjects And MethodsPatients scheduled for oral surgery with conscious sedation. Exclusions included ASA IV -V, inability to use the handset, opioid use and severe respiratory disease.InterventionsPatients were given intravenous propofol to a level of 1.0 microg/ml (reducing from 1.5 microg/ml) using a target controlled infusion system, they then controlled their sedation level by double-clicking a handset which on each activation increased the propofol concentration by 0.2 microg/ml.Main Outcome MeasuresOxygen saturation, patient satisfaction, and surgeon satisfaction.ResultsTwenty patients were recruited, 16 female and four male. Nineteen patients completed sedation and treatment successfully. Mean lowest oxygen saturation was 94%. No patients were over-sedated. All patients successfully used the system to maintain a level of sedation adequate for their comfort. Patient and surgeon satisfaction were consistently high.ConclusionsInitial experience with this novel system has confirmed safety, patient satisfaction and surgeon satisfaction.

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