• Anesthesia and analgesia · May 2002

    Continuous epidural infusion of 0.05% bupivacaine plus hydromorphone for labor analgesia: an observational assessment in 1830 parturients.

    • Raymond S Sinatra, Steven Eige, James H Chung, K Sam Chung, Ferne B Sevarino, Ana Lobo, Lee Fermo, and Carlos A Ocampo.
    • Department of Anesthesiology, Yale University School of Medicine, New Haven, Connecticut 06520-8051, USA.
    • Anesth. Analg. 2002 May 1;94(5):1310-1, table of contents.

    ImplicationsWe evaluated a continuous epidural infusion containing bupivacaine 0.05% plus the opioid hydromorphone in 1830 women requesting pain relief during labor and delivery. The infusion provided effective analgesia with minimal adverse events for patients differing in parity and at varying stages of labor. Pain relief was maintained in most patients without the need for epidural reinforcement with more concentrated doses of local anesthetic.

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