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- Isaac E Hall, Michael Kashgarian, Gilbert W Moeckel, and Neera K Dahl.
- Yale University School of Medicine, New Haven, CT, USA. isaac.hall@yale.edu
- Clin Nephrol. 2012 Jan 1;77(1):62-5.
AbstractAssociations between secondary focal segmental glomerulosclerosis and both obesity and obstructive sleep apnea have been previously described. Current theory suggests obesity induces glomerular hyperfiltration, leading to glomerulosclerosis. We describe a case of focal segmental glomerulosclerosis in the setting of severe obesity and obstructive sleep apnea with complete resolution of heavy proteinuria following treatment with bi-level positive airway pressure. The patient's proteinuria resolved completely with treatment of obstructive sleep apnea although the patient remained morbidly obese.
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