• Br. J. Haematol. · Feb 2007

    Outcomes of patients with haematological malignancies admitted to intensive care unit. A comparative review of allogeneic haematopoietic stem cell transplantation data.

    • Ziyi Lim, Antonio Pagliuca, Sylwia Simpson, Simon Cottam, Max Ervine, Aloysius Y L Ho, Stephen Devereux, and Ghulam J Mufti.
    • Haematological Medicine, Kings College London and Kings College Hospital, London, UK.
    • Br. J. Haematol. 2007 Feb 1;136(3):448-50.

    AbstractThe outcomes of 55 consecutive haemato-oncology patients admitted to the intensive care unit (ICU) were retrospectively analysed. Twenty-eight patients were admitted following haemopoietic stem cell transplantation (HSCT). Thirty-nine patients were admitted with respiratory failure, and all patients required respiratory support. Seventeen patients survived to be discharged from ICU, with an actuarial 1-year survival of 18%. Overall survival between patients who received intensive chemotherapy and those who underwent allogeneic HSCT was not significantly different (19% vs. 10%, P = 0.19). None of the nine myeloablative HSCT recipients survived (median survival: 9 d). Six of the 15 reduced-intensity conditioned HSCT recipients survived beyond 1 year (median survival: 1050 d, range: 438-1437).

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