• Muscle & nerve · Jan 2010

    Comparative Study

    Conduction block of peripheral nerve using high-frequency alternating currents delivered through an intrafascicular electrode.

    • D Michael Ackermann, Emily L Foldes, Niloy Bhadra, and Kevin L Kilgore.
    • Case Western Reserve University, Cleveland, Ohio, USA.
    • Muscle Nerve. 2010 Jan 1;41(1):117-9.

    AbstractMany diseases are characterized by undesired or pathological neural activity. The local delivery of high-frequency currents has been shown to be an effective method for blocking neural conduction in peripheral nerves and may provide a therapy for these conditions. To date, all studies of high-frequency conduction block have utilized extraneural (cuff) electrodes to achieve conduction block. In this study we show that high-frequency conduction block is feasible using intrafascicular electrodes.

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