• Methods Mol. Med. · Jan 2006

    Review

    Hyperpolarized gas and oxygen-enhanced magnetic resonance imaging.

    • Vu M Mai.
    • Department of Radiology, Evanston Northwestern Healthcare, IL, USA.
    • Methods Mol. Med. 2006 Jan 1;124:325-45.

    AbstractUnlike any other organ, imaging of lungs with magnetic resonance faces unique challenges owing to the complex microstructure and presence of gas-tissue interfaces. With the evolution of faster and stronger gradient systems leading to ultrafast imaging with ultrashort echo times, pulmonary magnetic resonance imaging (MRI) is no longer considered a technical challenge. In terms of functional evaluation, lungs are also associated with a unique function, viz. ventilation. Evaluation of ventilation is feasible with MRI either by using hyperpolarized noble gases or in an indirect fashion by performing oxygen-enhanced MRI. This chapter will provide an overview of these two methods.

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