• Simin Dashti-Khavidaki, Shirinsadat Badri, Seyedeh-Zahra Eftekharzadeh, Abbasali Keshtkar, and Hossein Khalili.
• Department of Clinical Pharmacy, School of Pharmacy, Tehran University of Medical Sciences, P.O. Box: 14155/6451, 1417614411 Tehran, Iran. dashtis@sina.tums.ac.ir
• Int J Clin Pharm. 2012 Oct 1;34(5):757-64.

BackgroundAs a common practice, medications are given in addition to nutrients through enteral catheters especially in critically ill patients. Nurses are primarily responsible to administer medications in this manner. The correct drug delivery via enteral tubes requires special skills.ObjectiveThis study was designed to evaluate effectiveness of clinical pharmacist-led educational program in progressing nurses' knowledge and practice regarding medications delivery via enteral catheters.SettingThis study has been performed in two teaching hospital affiliated to Tehran University of Medical Sciences.MethodsThis is a case-control, interventional study. At first, a knowledge and practice questionnaire regarding drug administration trough enteral feeding tube by intensivist nurses was prepared. This questionnaire was filled by each nurse at pre-intervention phase of the study. Then, the clinical pharmacists provided educational programs including preparing evidence-based booklet and classes for case group nurses. Nurses in case and control groups were evaluated again after 3 months. At pre- and post-intervention phases nurses were observed regarding their practice to administer drugs via enteral tubes as well.Main OutcomesMean scores of knowledge and practice questions as well as percent of nurses with correct answers were compared between pre- and post-intervention phases in case and control groups.ResultsThe mean scores of knowledge and practice questions significantly increased in the case group but decreased or remained unchanged in the control group. In contrast to control group, the percent of nurses with correct answers to each domain of knowledge and practice questions increased significantly in the case group.ConclusionThis study showed that nurses did not have sufficient baseline knowledge about rules of drug administration via enteral feeding tubes; however, integrated educational program by clinical pharmacists that focus on promoting correct administration of drugs via enteral feeding catheters significantly improved knowledge and practice of nurses. A theory-practice gap was found in this study that may be related to the authority of physicians not nurses in ordering rules for medication administration through enteral catheters.

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