- 
          
          Paediatric anaesthesia · Jun 2004 Randomized Controlled Trial Comparative Study Clinical TrialA comparison between single- and double-breath vital capacity inhalation induction with 8% sevoflurane in children.- Kok-Yuen Ho, Wee-Leng Chua, Serene S T Lim, and Agnes S B Ng.
- Department of Anaesthesia (Paediatrics), KK Women's and Children's Hospital, Singapore. hokokyuen@yahoo.com.sg
- Paediatr Anaesth. 2004 Jun 1;14(6):457-61.
 BackgroundThis study was conducted to determine if a double-breath (DB) vital capacity (VC) rapid inhalation induction using immediate high-inspired concentration of sevoflurane is as well tolerated as a single-breath (SB) technique and if it results in a shorter induction time.MethodsA total of 104 children, ASA I-II, 6 year and above, undergoing elective surgery were randomly assigned to two groups: SB VC inhalation induction or DB VC inhalation induction with 8% sevoflurane in 66% nitrous oxide. The induction time, complications (cough, laryngospasm, breath-hold, movement, salivation) and level of satisfaction were documented.ResultsInduction was significantly faster in the DB group (41 +/- 9 s) compared with the SB group (50 +/- 14 s). DB inhalation induction was associated with fewer complications (15.4%) than the SB technique (50%).ConclusionsDouble-breath VC inhalation induction with 8% sevoflurane is as well tolerated as a SB technique and results in a faster onset of anaesthesia. Notes
 Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes- Simple formatting can be added to notes, such as *italics*,_underline_or**bold**.
- Superscript can be denoted by <sup>text</sup>and subscript<sub>text</sub>.
- Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens-or asterisks*.
- Links can be included with: [my link to pubmed](http://pubmed.com)
- Images can be included with: 
- For footnotes use [^1](This is a footnote.)inline.
- Or use an inline reference [^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..