• Curr Opin Pulm Med · Jul 2011

    Review

    Management of malignant pleural effusions.

    • Francisco Rodriguez-Panadero and Beatriz Romero-Romero.
    • Unidad Médico-Quirúrgica de Enfermedades Respiratorias (UMQER) and Instituto de Biomedicina de Sevilla (HUVR-IBiS), Sevilla, Spain. frpanad@ono.com
    • Curr Opin Pulm Med. 2011 Jul 1;17(4):269-73.

    Purpose Of ReviewMalignant pleural effusions (MPEs) are one of the most common problems faced by clinicians and, since there is no optimum treatment available, they deserve efforts aimed to improve their management.Recent FindingsWe have reviewed the most recent articles regarding treatment of MPE, with special emphasis on pleurodesis and indwelling pleural catheter placement. Although iodopovidone, silver nitrate and doxycycline are useful, talc continues to be the most effective agent available for pleurodesis. Use of calibrated talc with large particle size is now firmly established, in order to prevent complications. Indwelling pleural catheters are gaining general acceptance, and they are currently a valid option for patients with lung entrapment or those who have a previous failed pleurodesis. Advances in translational medicine related to this topic are also described.SummaryThe above results may contribute to improve significantly management of patients with malignant pleural effusions, especially those with advanced disease who are not suitable for pleurodesis procedures.

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