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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of continuous and intermittent administration of extradural bupivacaine for analgesia after lower abdominal surgery.
- L A Duncan, M J Fried, A Lee, and J A Wildsmith.
- Department of Anaesthetics, Royal Infirmary, Edinburgh.
- Br J Anaesth. 1998 Jan 1;80(1):7-10.
AbstractWe have compared intermittent bolus and continuous infusion of extradural local anaesthetic for pain relief in a randomized, double-blind study of 48 patients who underwent major abdominal gynaecological surgery. Each patient received 5 ml of 0.375% bupivacaine hourly, either as a bolus over 5 min or as a constant infusion. Patients who received the intermittent administration technique maintained a more extensive sensory block, reported marginally better analgesia and had a lower requirement for rescue medication. The intermittent bolus technique was not associated with an increase in side effects.
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