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- Torijaun Dallas, Ian Welsby, Brandi Bottiger, Carmelo Milano, Mani Daneshmand, and Nicole Guinn.
- From the Department of Cardiothoracic Anesthesiology, Duke University Medical Center, Durham, North Carolina.
- A A Case Rep. 2015 May 15;4(10):140-2.
AbstractWe present the case of a 53-year-old female Jehovah's Witness with nonischemic cardiomyopathy who successfully underwent a bloodless heart transplantation using fibrinogen concentrate (RiaSTAP; CSL Behring, King of Prussia, PA) and other blood-conservation methods. With a multidisciplinary team and the use of preoperative erythropoietin-stimulating drugs, normovolemic hemodilution, cell salvage, and pharmacotherapy to prevent and treat coagulopathy, we were able to maintain hemoglobin levels greater than 11 g/dL without the need for blood transfusion. We conclude that orthotopic heart transplants may be performed successfully in select Jehovah's Witness patients using standard and novel blood conservation methods.
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