• Int J Obstet Anesth · May 2016

    Review

    Cytokines in the perinatal period - Part II.

    • A Chau, J C Markley, J Juang, and L C Tsen.
    • Division of Obstetric Anesthesia, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Department of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia, Vancouver, BC, Canada. Electronic address: antonchau1@gmail.com.
    • Int J Obstet Anesth. 2016 May 1; 26: 48-58.

    AbstractA contemporary, robust immunologic explanation for common obstetric conditions remains elusive; why some pregnant women are more susceptible to developing preeclampsia or preterm labor is not completely understood. We explore the immunology behind four important and commonly encountered pregnancy-related conditions: preeclampsia, recurrent miscarriage, preterm labor and gestational diabetes. For each condition, we summarize the current understanding of cytokines implicated in the pathogenesis, discuss the impact of anesthesia and analgesia on selected cytokine profiles, and suggest potential opportunities for clinical and research interventions.Copyright © 2016 Elsevier Ltd. All rights reserved.

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