• Pain · Feb 1996

    Randomized Controlled Trial Clinical Trial

    A new method of recording somatosensory evoked potentials by randomized electrical tooth stimulation with 6 levels of intensity.

    • M Umino, T Ohwatari, and M Nagao.
    • Department of Geriatric Dentistry, Faculty of Dentistry, Tokyo Medical and Dental University, Japan.
    • Pain. 1996 Feb 1;64(2):269-76.

    AbstractDental somatosensory evoked potentials (SEPs) corresponding to the stimulus intensity levels were recorded at 6 different levels of intensity presented in a randomized order. The relationships between the amplitude of the late SEP component with latency between 150 and 300 msec and each stimulus intensity level were also compared in conditions of randomized intensity and constant intensity. The amplitude of the late component increased significantly with the increased stimulus intensity both in the randomized and constant intensity stimulation. The amplitude of the late component in the randomized stimulation with a 1-sec interstimulus interval (ISI) increased in the same manner as that in the constant intensity condition with a 1-sec ISI. The randomized stimulation with the prolonged ISI increased the amplitude of the late component. The latency of the late positive component significantly increased with the randomized stimulation with a 3-sec ISI. This phenomenon might be attributable to the psychological contamination. SEP recording in the randomized dental stimulation with a 1-sec ISI may have applications in neuropharmacological research or physiological research on pain and evaluation of the effects of analgesics, anesthetics, acupuncture and transcutaneous electrical nerve stimulation (TENS).

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