• J M Bergstein, D P Slakey, J R Wallace, and M Gottlieb.
• Department of Family Medicine and Community Health, Medical College of Wisconsin, Milwaukee, USA.
• Ann Emerg Med. 1996 Jan 1;27(1):39-42.

Study ObjectiveTo determine whether posttraumatic hypothermia is associated with hemorrhage or with resuscitation.MethodsWe used a sequential hemorrhage-resuscitation rat model. Rats were subjected to hemorrhage (30 mL/kg), then 1 hour of shock, followed by 2:1 crystalloid/blood resuscitation (60 mL/kg) at ambient temperature. A control group underwent neither hemorrhage nor resuscitation.ResultsWe recorded core temperature and blood pressure every 10 minutes. Temperature drop averaged 3.4 degrees C and was fastest during hypotensive shock. Rate of temperature change correlated with blood pressure (beta = .0102, P < .001), shock phase (beta = .4504, P = .041), and blood pressure during shock phase (beta = .0116, P < .001), but not with resuscitation phase or with duration of shock or resuscitation. Three of 14 rats died during shock, none during resuscitation. An increase in temperature was noted in 1 of 14 rats during shock and in 7 of 11 rats during resuscitation.ConclusionHemorrhage-associated hypothermia occurs during hypotensive shock, not during fluid resuscitation.

20 keywords...

hide…