• Br J Anaesth · Sep 1987

    Case Reports

    Malignant hyperpyrexia and isoflurane. A case report.

    • D W Thomas, V J Dev, and M J Whitehead.
    • Department of Anaesthetics, Morriston Hospital, Cwmrhydyceirw, Swansea.
    • Br J Anaesth. 1987 Sep 1;59(9):1196-8.

    AbstractMalignant hyperpyrexia developed, and was successfully treated, in a 50-year old man undergoing pyelolithotomy. Early diagnosis with the assistance of end-tidal carbon dioxide monitoring facilitated prompt treatment with i.v. dantrolene. A positive muscle biopsy subsequently confirmed the diagnosis. The only likely triggering agent used was isoflurane.

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