• Braz J Infect Dis · Feb 2005

    Case Reports

    Dapsone syndrome with acute renal failure during leprosy treatment: case report.

    • Edson Nogueira Alves-Rodrigues, Luciano Correa Ribeiro, Margareth Dióz Silva, Arley Takiuchi, and Cor Jesus Fernandes Fontes.
    • Medical Clinics Department, Centre of Infectious Diseases and Tropical Diseases Research of Mato Grosso, Júlio Müller Hospital, Cuiabá, MT, Brazil.
    • Braz J Infect Dis. 2005 Feb 1;9(1):84-6.

    AbstractDapsone syndrome is a rare hypersensitivity reaction to dapsone and is characterized by high fever, papular or exfoliative dermatitis, progressing to liver toxicity and generalized lymphadenopathy, resembling a mononucleosis infection. We report a patient who developed acute renal failure, as well as other complications characteristic of dapsone syndrome, during leprosy treatment. Renal involvement had not been previously described as a dapsone syndrome feature.

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