• Indian J Gastroenterol · Apr 2000

    Case Reports

    Dapsone hypersensitivity syndrome with coexisting acute hepatitis E.

    • A Chogle, A Nagral, A Soni, S Agale, and Z Jamadar.
    • Kasturba Hospital for Infectious Diseases, Sane Guruji Marg, Mumbai.
    • Indian J Gastroenterol. 2000 Apr 1;19(2):85-6.

    AbstractA 14-year-old girl presented with fever, generalized lymphadenopathy, skin rash and hepatitis after starting dapsone. All abnormalities reversed with institution of prednisolone therapy after discontinuation of dapsone. The hepatic involvement was of hepatocellular type; it was associated with IgM anti-HEV antibodies, suggesting coexisting acute hepatitis E. We believe a causal link between the hepatotrophic viruses and dapsone hypersensitivity syndrome could exist.

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