• Revue médicale suisse · Dec 2009

    [Update on the management of severe traumatic brain injury].

    • Mauro Oddo and Yvan Gasche.
    • Service de médecine intensive adulte, Département des centres interdisciplinaires et logistique médicale, CHUV, 1011 Lausanne. mauro.oddo@chuv.ch
    • Rev Med Suisse. 2009 Dec 9;5(229):2506-10.

    AbstractPrognosis after severe traumatic brain injury (TBI) is determined by the severity of initial injury and secondary cerebral damage. The main determinants of secondary cerebral damage are brain ischemia and oedema. Traumatic brain injury is a heterogeneous disease. Head CT-scan is essential in evaluating initial type of injury and severity of brain oedema. A standardised approach based on prevention and treatment of secondary cerebral damage is the only effective therapeutic strategy of severe TBI. We review the classification, pathophysiology and treatment of secondary cerebral damage after severe TBI and discuss the management of intracranial hypertension, cerebral perfusion pressure and brain ischemia.

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