• Int J Occup Med Environ Health · Jan 2009

    Ambient sulphur dioxide exposure and emergency department visits for migraine in Vancouver, Canada.

    • Mieczyslaw Szyszkowicz, Brian H Rowe, and Gilaad G Kaplan.
    • Population Studies Division, Health Canada, Ottawa, ON, Canada. mietek_szyszkowicz@hc-sc.gc.ca
    • Int J Occup Med Environ Health. 2009 Jan 1;22(1):7-12.

    ObjectivesAmbient exposure to sulphur dioxide (SO2) has been previously associated with emergency department (ED) visits for migraine headaches. In the present study, the objective was to examine the relationship between ED visits for migraine and ambient sulphur dioxide concentrations.Design And MethodsThis was a time-series study of 1059 ED visits for migraine (ICD-9: 346) recorded at a Vancouver hospital between 1999 and 2003 (1 520 days). Air pollution levels of SO2 were measured by fixed-site monitoring stations. The generalized linear mixed models technique was applied to regress daily counts of ED visits for migraine on the levels of the pollutant after adjusting for meteorological conditions: temperature and relative humidity. The analysis was stratified by season and gender.ResultsPositive and statistically significant correlations were observed for SO2 exposure and ED visits for migraine for females during colder months (October-March). The percentage increase in daily visits was 16.8% (95% CI: 1.2-34.8) for a 4-day average (of daily mean concentrations) SO2 level, for an interquartile range (IQR) increase of 1.9 ppb.ConclusionsOur findings provide additional support for a consistent correlation between migraine headache and air pollution (SO2).

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