• Der Unfallchirurg · Aug 2014

    Review

    [Biomarkers in pediatric polytrauma].

    • H Andruszkow, R Pfeifer, K Horst, P Kobbe, H-C Pape, and F Hildebrand.
    • Klinik für Unfall- und Wiederherstellungschirurgie und Harald Tscherne Forschungslabor, Universitätsklinikum der RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Deutschland, handruszkow@ukaachen.de.
    • Unfallchirurg. 2014 Aug 1; 117 (8): 679-85.

    BackgroundTrauma represents one of the leading causes of death in children. Beside an injury pattern that differs from adult trauma patients, children seem to develop multiple organ dysfunction syndrome (MODS) less frequently. Compared to adult MODS, pediatric MODS has also been described to occur earlier in the posttraumatic course.MethodBiomarkers for early identification of patients at high-risk for posttraumatic complications are of high clinical relevance. However, little is known from clinical studies about the relevance of biomarkers during the posttraumatic course.AimTherefore, the purpose of this review is to summarize current knowledge on this topic in order to investigate the prognostic significance of different parameters.

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