• Der Unfallchirurg · Mar 2007

    Case Reports

    [Perioperative coagulation management controlled by thrombelastography. Clinical implementation illustrated by reference to a case of acquired coagulopathy following aortic stab injury].

    • R Grashey, P Mathonia, W Mutschler, and B Heindl.
    • Klinik für Anaesthesiologie, Ludwig Maximilians Universität München, Nussbaumstrasse 20, 80336 Munich. bernhard.heindl@med.uni-muenchen.de
    • Unfallchirurg. 2007 Mar 1;110(3):259-63.

    AbstractUncontrolled bleeding is one of the main reasons for a lethal outcome of severe trauma. Loss, consumption and dilution of clotting factors and platelets induce a complex acquired coagulopathy. Beside surgical control of bleeding, early and precise coagulation therapy is essential for successful treatment. We report on a patient whose life-threatening bleeding and perioperative coagulopathy after a knife injury to the aorta was successfully treated by surgical control of the bleeding and subsequent targeted coagulation therapy with factor concentrates and fresh-frozen plasma. The coagulopathy was diagnosed and managed by means of bed-side thrombelastography.

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