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- R Grashey, P Mathonia, W Mutschler, and B Heindl.
- Klinik für Anaesthesiologie, Ludwig Maximilians Universität München, Nussbaumstrasse 20, 80336 Munich. bernhard.heindl@med.uni-muenchen.de
- Unfallchirurg. 2007 Mar 1;110(3):259-63.
AbstractUncontrolled bleeding is one of the main reasons for a lethal outcome of severe trauma. Loss, consumption and dilution of clotting factors and platelets induce a complex acquired coagulopathy. Beside surgical control of bleeding, early and precise coagulation therapy is essential for successful treatment. We report on a patient whose life-threatening bleeding and perioperative coagulopathy after a knife injury to the aorta was successfully treated by surgical control of the bleeding and subsequent targeted coagulation therapy with factor concentrates and fresh-frozen plasma. The coagulopathy was diagnosed and managed by means of bed-side thrombelastography.
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