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- F Wallet, A Didelot, B Delannoy, V Leray, and C Guerin.
- Service de réanimation médicale, hôpital de la Croix-Rousse, CHU de Lyon, 103, grande rue de la Croix-Rousse, 69004 Lyon, France. Electronic address: florent.wallet@chu-lyon.fr.
- Ann Fr Anesth Reanim. 2014 Sep 1; 33 (9-10): 530-2.
AbstractWe report the case of a 55-year-old man without significant medical history admitted to the ICU for a progressive paralysis mimicking life-threatening tetanus. Evolution with classical tetanus treatment was negative, with the need for ventilator support and worsening condition being life threatening. Uncommon evolution revealed a rare glycin antibody-associated hyperekplexia (progressive encephalomyelitis with rigidity syndrome). Patient dramatically improved with immunosuppressive therapy including plasmatic exchanges, cyclophasmid and high dose corticoid infusions. Intensivists should be aware of this very rare syndrome whose treatment is the opposite of tetanus while presentation is very close. Optimal and treatment could lead to prolonged survival.Copyright © 2014 Société française d’anesthésie et de réanimation (Sfar). Published by Elsevier SAS. All rights reserved.
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