• Dtsch. Med. Wochenschr. · Jan 2013

    Review

    [Biomarker screening for early detection of cancer].

    • G J Wiedemann.
    • Klinik für Innere Medizin, Gastroenterologie und Onkologie, Oberschwabenklinik, St. Elisabeth, Ravensburg. guenther.wiedemann@oberschwabenklinikmann@oberschwabenklinik.de
    • Dtsch. Med. Wochenschr. 2013 Jan 1;138(1-2):43-5.

    AbstractThe question of when a certain concentration of a serum biomarker turns into a tumor marker, i. e. an objectively verifiable criterion for tumor diagnosis, leads to the analysis of the specificity (a measure of the proportion of correctly identified healthy individuals), sensitivity (a measure of the proportion of correctly recognized cancer patients), and precision (positive predictive value). Or in short: a tumor marker is specific if no healthy individual has one. This constitutes the problem: The serum concentrations of biomarkers of cancer patients and healthy subjects overlap. Healthy individuals occasionally have "tumor markers" and cancer patients in turn sometimes express inconspicuous biomarkers.© Georg Thieme Verlag KG Stuttgart · New York.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…