• An Med Interna · Jan 2002

    Review

    [Sepsis and septic shock: a turmoil of inflammatory mediators with difficult therapeutic management].

    • H J Durán Giménez-Rico, M A Aller Reyero, L Lorente Ruigómez, L Durán Giménez-Rico, J Arias Pérez, and H Durán Sacristán.
    • Departamento de Cirugía, Facultad de Medicina, Universidad Complutense, Madrid.
    • An Med Interna. 2002 Jan 1;19(1):35-43.

    AbstractSepsis and septic shock continue being a topic of enormous interest for their high frequency, and for not existing a decrease in the figures of mortality in spite of the new acquired knowledges relation with their physiopathology and the advances arisen in the diverse applied treatments. The purpose of the present study is to update the present notions in the specialized literature, trying to summarize the complex existent interaction among different mediators of double character: exogenous and endogenous, and to enunciate the possible causes for those that the novel treatments applied in the sepsis continue not to be very promising.

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